Ibsrela (Tenapanor)

Ibsrela, known generically as tenapanor, is a medication used for treating irritable bowel syndrome with constipation (IBS-C) in adults. It functions by inhibiting the sodium/hydrogen exchanger 3 (NHE3), which leads to increased water secretion in the intestine and colon, facilitating easier stool passage.

How to Take Ibsrela

• Ibsrela should be taken exactly as prescribed by your doctor.
• The typical dosage involves taking one tablet orally, twice a day.
• These tablets should be taken immediately before breakfast or the first meal of the day and immediately before dinner.
• If you miss a dose, skip it and take the next dose at the regular time. Do not take two doses at the same time.

Possible Side Effects

• The most common side effect of Ibsrela is diarrhea, which can sometimes be severe. If you experience severe diarrhea, you should stop taking Ibsrela and consult your doctor.
• Other common side effects include swelling or a feeling of fullness or pressure in the abdomen (distension), gas (flatulence), and dizziness.

Safety and Precautions

• It's important to inform your doctor about all your medical conditions before taking Ibsrela, especially if you are pregnant, planning to become pregnant, or breastfeeding.
• The safety and effectiveness of Ibsrela in children under 18 years of age have not been established.

Storage Instructions

• Store Ibsrela tablets at room temperature, between 68°F and 77°F (20°C and 25°C).
• Keep the tablets in their original container, protected from moisture, and keep the container tightly closed in a dry place.
• Do not repack the tablets into another container.

Ingredients

• Active ingredient: tenapanor hydrochloride
• Inactive ingredients include colloidal silicon dioxide, hypromellose, and several others.

Ibsrela is cheaper in Canada due to government regulations that control drug prices, which is not the case in the United States.

For detailed information and updates, it's recommended to consult healthcare professionals or check with pharmacies in the respective countries for current pricing.

Ibsrela should be taken immediately before breakfast or the first meal of the day and immediately before dinner.